![]() ![]() "What that means is melatonin can shift your sleep-brain rhythm based on when you take it," Dr. The second is what's called a chronotropic effect. The first is a weak sleep-inducing effect that only some people respond to. The hormone has two effects on the brain. In the U.S., you can buy melatonin as a supplement, but it's available as prescription-only medication elsewhere in the world. Melatonin is a hormone produced naturally in our brains every day, regulating wakefulness as levels go up at night time and gradually go down early in the morning. It's better to take pills with only the active ingredients you need. ![]() You can pick whatever you feel the most comfortable with, including generics.Ī Note About Nighttime Painkillers: Skip antihistamine meds that also include ibuprofen ( Advil PM) or acetaminophen ( Tylenol PM) unless you're experiencing aches and pains. Bollu says that the bottomline is that the products all contain the same active ingredients. If you suffer from restless leg syndrome, antihistamines can even make symptoms worse, so talk to your doctor before using any. While these drugs may make you feel drowsy, they can also lead to side effects like dizziness, dry mouth, and memory or cognition problems and they're not designed for long-term use. "They antagonize the alerting chemical called histamine in one particular region of the brain, and by antagonizing histamine, it makes people sleepy." "In the doses that are available over the counter, antihistamines are relatively safe and they work for a lot of people," says Pradeep Bollu, M.D., a board-certified sleep specialist and neurologist with MU Health Care. (The allergy medication Benadryl also contains diphenhydramine, which is why it can make you sleepy.) Here's what you can expect from each type: AntihistaminesĬommon sleep meds like Zzzquil and Unisom contain antihistamines like diphenhydramine and doxylamine as the active ingredients. Most OTC sleep aids induce sleep using antihistamines, but you'll also find popular supplements like melatonin and valerian in the pharmacy aisles. Sleep apnea, mood disorders, and thyroid problems can all cause sleeplessness. If you're experiencing chronic insomnia, visit your primary care provider to figure out it's a sign of something more serious. Doing so can cause side effects like persistent drowsiness, confusion, memory problems, dry mouth, and urinary issues. OTC sleep aids aren't habit-forming in the sense that your body won't become physically dependent on them, but they're also not designed for regular, long-term use.
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